Kolagit and Loss of Healing Momentum
Jakarta, Gita Adinda Nasution, a student in North Sumatra to be a new 'celebrity' in the diabetes patient group. He flooded Kolagit order, his sugar cane creations that claimed efficacious lowering the blood sugar content.
Not in the know exactly what the composition contained in the herb's ingredients, Gita itself still keep it a secret. A little leak from it, Kolagit has sugar cane and has a taste like coffee. With that argument also named Kolagit, stands for Coffee Gula Gita. "Kolagit also improves the role of pancreas, kidneys, and stomach damaged by complications of diabetes," said Gita who admitted to have tested the benefits of Kolagit on a collection of mice in the laboratory, when detikHealth contacted some last time, as written on Friday (28/2/2014 ).
Regardless of whether or not Gita claims, Kolagit's phenomenon warns that some of the diabetes drugs needed to be used today also come from plants. Certainly, after passing a series of clinical trials by several scientists as well as undergoing changes throughout the decades.
One of them is Metformin, a biguanida group diabetes drug that comes from the Galega officinalis plant. This flowering plant is widely found in Europe and has a popular name French Lilac. Starting from several thousand th. ago, this plant traditionally used to cure polyuria (lots of urine) and halitosis (bad breath), 2 health problems associated with the sign of diabetes.
Emil Warner and James Bell first discovered the Metformin content of the plant on th. 1922, with the chemical name 'N'-dimethylguanidine. The impact of hypoglycemic or decreased blood sugar content of this drug is observed in rabbits in th. 1929, in tests conducted by Slotta and Tschesche.
From then on, some scientists believe that Metformin is so likely to be developed into a diabetes drug. Unfortunately, these findings are immersed in the excitement of insulin discovery in th. 1922 by Canadian scientist Frederick Banting, as well as his assistant, Charles Best. Insulin at the time was seen as a miracle that saved millions of people from the 'death sentence' of diabetes. Thus the need, some until Banting and his colleagues eliminate the insulin patent. Upon this finding, Banting was also awarded the Nobel Prize in medicine in 1923.
Metformin was re-glimpsed after its adoption in humans approved in Britain in 1950, as well as in Canada in 1972. The United States only agreed in 1995, when the pharmaceutical company Bristol-Myers Squibb produced the drug under the name Glucophage. From then on, Metformin became the most widely prescribed diabetes drug for diabetes, which is about 120 million recipes / year. "Until now, Metformin has become the most widely used drug of choice for diabetes in all the world," said Dr. Dante Saksono Harbuwono, SpPD, PhD, diabetes researcher from the Endocrine Metabolic Division, Department of Internal Medicine, Faculty of Medicine Campus Indonesia. Of herbs also, the most advanced diabetes drug that is SGLT2 (Sodium Glucose co-Transferase 2) Inhibitor originated. The group of gliflozine drugs, which have not been widely used in Indonesia, have also come from the bark of some kind of apple tree grown in France.
Similar to metformin, the SGLT2 Inhibitor is also a long journey since it is found in plants in th. 1835, to agree on its use in humans. Some drugs from this group, canagliflozine and dapagliflozine are newly approved for human use in the United States by 2013.
'Jump to Conclusion'Reading from the history of Metformin and SGLT2 Inhibitor, diabetes drugs do not come out just like that from nature. Previously claimed to be a drug, useful content of plants first through a series of tests. From laboratory testing, to preclinical testing in animals or to clinical trials in humans. Not enough is just effectual, a good medicine should be safe, tolerable, and as little as possible at its peril. Proving it is not random, it should involve scientists with internationally recognized Good Clinical Practice (GCP) certificates. "What goes on, some scientists do 'jump to conclusion' when studying herbs, conclude efficaciously, without knowing the risks and work steps," said Dr. Dante, who holds the GCP certificate and many studies of herbs for diabetes.
Usually there are 'jumps' in concluding the results of herbal research, according to Dr. Dante can menjerumuskan patients. Premature claims make patients expect so much, then leave standard healing. When a herb that has not been tested is in fact not efficacious or has an unintended risk, the patient has lost the momentum of healing because the disease is worse.
The same jump took place also on Kolagit, when the efficacy of diabetes drug just proved through testimony of some patients who had tried diabetes. Nor can it be said to be a new finding, because the antidiabetic benefits of sugarcane crops have been thoroughly started for several decades. first. "Sugar cane indeed contains saccharans, polysaccharide compounds that have antidiabetic properties.Japanese scientist, Michiko Takahashi had studied them in mice and published in the journal Planta Medica in 1985," said Prof. Dr. CJ Soegihardjo, Apt, a researcher of traditional medicine from the Faculty of Pharmacy Sanata Campus Dharma Yogyakarta.
With the exception of sugar cane, some of the herbs that had been thoroughly diagnosed with diabetes can be examined through the link: Infographics: Some Plants Meticulous So Diabetes Drugs (up / vit)
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Kolagit and Losing the Momentum of Medicine Jakarta, Gita Adinda Nasution, a student in North Sumatra became a new 'celebrity' among diabetic patients. He flooded Kolagit order, his sugar cane potion creations that claimed efficacious to lower blood sugar levels. It is not known exactly what the composition contained in the herb, Gita itself still keep it a secret. A little leak from it, Kolagit contains sugar cane and has a taste like coffee. For that reason also called Kolagit, stands for Coffee Gula Gita. "Kolagit also improves the function of the pancreas, kidneys, and stomach damaged by complications of diabetes," said Gita who claimed to have tested the efficacy of Kolagit in a group of mice in the laboratory, when contacted detikHealth recently, as written on Friday (28/2/2014 ). Regardless of whether or not Gita claims, Kolagit's phenomenon reminds us that some of the most important diabetes drugs used today are also from plants. Obviously, after going through a series of clinical trials by scientists and having developed for decades. One of them is Metformin, a biguanida diabetes drug derived from the Galega officinalis plant. This flowering plant is widely found in Europe and has a popular name French Lilac. Since thousands of years ago, this plant has traditionally been used to treat polyuria (lots of urine) and halitosis (bad breath), 2 health problems associated with diabetes symptoms. Emil Warner and James Bell first discovered the content of Metformin from the plant in 1922, with the chemical name 'N'-dimethylguanidine. The hypoglycemic effect or lowering of blood sugar levels of this drug was observed in rabbits in 1929, in an experiment conducted by Slotta and Tschesche. Since then, scientists believe that Metformin is very potential to be developed as a diabetes drug. Unfortunately, this discovery sank in the midst of a rush of insulin discovery in 1922 by Canadian scientist Frederick Banting and his assistant, Charles Best.Insulin at the time was considered a miracle that saved millions of people from the 'death sentence' of diabetes. So important, so that Banting and his colleagues eliminate the insulin patent. On this finding, Banting was awarded the Nobel Prize in medicine in 1923. Metformin was again glimpsed after its use in humans was approved in Britain in 1950, and in Canada in 1972. The United States only approved in 1995, when the pharmaceutical company Bristol-Myers Squibb produced the drug this with the name Glucophage. Since then, Metformin has become the most widely prescribed diabetes drug for diabetes, which is about 120 million prescriptions / year. "Until now Metformin has become the first-line drug of choice most widely used for diabetes worldwide," said Dr. Dante Saksono Harbuwono, SpPD, PhD, diabetes researcher from the Endocrine Metabolic Division, Department of Internal Medicine, Faculty of Medicine, University of Indonesia. -the plant also, the latest diabetes drug SGLT2 (Sodium Glucose co-Transferase 2) Inhibitor originated. Gliflozine group drugs, which have not been widely used in Indonesia, originally also came from the bark of an apple tree that grows in France. Just like metformin, the SGLT2 Inhibitor also travels long since it was discovered in plants in 1835, until it was approved for its use in humans. Some drugs of this class, canagliflozine and dapagliflozine are newly approved for use in humans in the United States by 2013. 'Jump to Conclusion' Read from the history of Metformin and SGLT2 Inhibitors, diabetes drugs do not just appear from nature. Prior to being claimed as a drug, the nutritious content of the herbs first through a series of tests. Starting from experiments in the laboratory, to preclinical testing in animals and clinical trials in humans. Not only enough efficacy, good medicine should also be safe, tolerable, and as little as possible have side effects. Prove it is not arbitrary, it should involve scientists with internationally recognized Good Clinical Practice (GCP) certificates. "What happens, some scientists do a 'jump to conclusion' when researching herbs, concludes effectively, without knowing the side effects and how it works," said Dr. Dante, who also holds a GCP certificate and researches many herbs for diabetes. Often there are 'jumps' in concluding the results of herbal research, according to Dr. Dante can plunge the patient. Premature claims make patients expect too much, then abandon standard treatment. When the untested herb turns out to be ineffective or has unexpected side effects, the patient has lost the momentum of treatment because his illness has worsened. Such a jump occurs also in Kolagit, when its efficacy as a diabetes drug is only proven through testimony of some diabetic patients who have tried it. Also can not be called as a new finding, because the efficacy of antidiabetes sugar cane plant has been studied since tens of years earlier. "Sugar cane contains saccharans, polysaccharide compounds that have antidiabetic properties.Japanese scientist, Michiko Takahashi had studied them in mice and published in the journal Planta Medica in 1985," said Prof. Dr. CJ Soegihardjo, Apt, a researcher of traditional medicine from the Faculty of Pharmacy, Sanata Dharma University, Yogyakarta . In addition to sugar cane, some of the herbs that have been studied as a diabetes drug can be seen through the following links: Infographics: Some Plants Researched as Diabetes Drugs (up / vit) "
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